Genomic Medicine
Where:
Medical Education Center, Rm 334
Longwood Avenue
When:
Audience:
This course is targeted to medical students, biomedical scientists, biomedical engineers and instructors of future genomic medicine and related courses. The world-class faculty assembled for this course has been specifically targeted for this audience by virtue of their leadership in this domain and communication/teaching skills
Format: Lectures twice a week with weekly review section. 4 problem sets (including hands-on bioinformatics), and a final project)
Pre-requisite: HST 160 or introductory genetics or instructor’s permission.
Enrollment limited to 30
Mycourses: all lectures available through the myCourses website (please contact course instructors if you do not have access).
Some of the questions addressed:
-
How can diagnosis and the diagnostic process be changed today?
-
How do our prognostic abilities change?
-
What real benefits of genomics can be anticipated in the near future in terms of new drugs and treatments?
-
What is clustering and classification and how do I do it?
-
Which strategies to date have been the most successful?
-
How does one manage the deluge of clinically relevant genomic data?
-
What constitutes a genomic clinical trial?
-
What are the useful features of alternative genomic technologies today and for the near future?
-
What are the different kinds of genomic informational resources and databases? Are they useful and how?
-
How can the drug discovery process make better use of genomic information?
-
What are the ethical individual and corporate challenges ahead?
-
What are the key limitations we face?
Texts:
Genomes (2nd edition), TA Brown
Microarrays for an Integrative Genomics, I. Kohane, A. Kho, A. Butte
Guiding Icarus: Merging Bioethics With Corporate Interests, R. Dhanda, P. Reilly
And 20+ papers
Available also in Boston at Quantum Books and the Harvard Medical Coop
Contact:
Course Director: Isaac Kohane, MD, PhD isaac_Kohane@harvard.edu
Website: genomicmedicine.chip.org
