Genomic Medicine

HST 586

Where:

Medical Education Center, Rm 334

Longwood Avenue

When:

12:30-2 pm Tuesday/Thursday

Audience:

This course is targeted to medical students, biomedical scientists, biomedical engineers and instructors of  future genomic medicine and related courses. The world-class faculty assembled for this course has been specifically targeted for this audience by virtue of their leadership in this domain and communication/teaching skills

Format: Lectures twice a week with weekly review section. 8 problem  sets, no exams.

Pre-requisite: HST 160 or introductory genetics or instructor’s permission.

Enrollment: limited to 30

Schedule

Some of the questions addressed:

  • What real benefits of genomics can be anticipated in the near future in terms of new drugs and treatments?
  • Which strategies to date have been the most successful?
  • How can diagnosis and the diagnostic process be changed today?
  • How do our prognostic abilities change?
  • How does one manage the deluge of clinically relevant genomic data?
  • What constitutes a genomic clinical trial?
  • What are the useful features of alternative genomic technologies today and for the near future?
  • What are the different kinds of genomic informational resources and databases? Are they useful and how?
  • How can the drug discovery process make better use of genomic information?
  • What are the ethical individual and corporate challenges ahead?
  • What are the key limitations we face?

Texts:

Genomes (2nd edition), TA Brown

Microarrays for an Integrative Genomics, I. Kohane, A. Kho, A. Butte

Guiding Icarus: Merging Bioethics With Corporate Interests, R. Dhanda, P. Reilly

And 20+ papers

Available also in Boston at Quantum Books and the Harvard Medical Coop

Contact:

Course Director: Isaac Kohane, MD, PhD isaac_kohane@harvard.edu

Website: genomicmedicine.chip.org